Chair: Maja Trošt (1), Daniela Perani (2)
(1) Department of Neurology, University Medical Centre, Ljubljana, Slovenia
(2) San Raffaele University, Division of Neuroscience, San Raffaele Scientific Institute, Nuclear Medicine Unit, San Raffaele Hospital, Milan, Italy
Functional brain imaging with positron emission tomography (PET) and various radioligans is becoming widely used diagnostic tool in clinical neurology and psychiatry enabling early diagnosis and improved diagnostic accuracy in neurodegenerative brain disorders. In dementia and in movement disorders with or without cognitive impairment, metabolic brain imaging with fluorodeoxyglucose/PET shows us the distribution of the neurodegenerative processes.
In parkinsonian disorders and in some dementia syndromes, specific network analyses of metabolic brain imaging with fluorodeoxyglucose gained specific metabolic patterns that represent a metabolic brain biomarker of the disease. White matter connections collectively form the connectome and provide the underpinnings of distributed patterns of brain activity. The connectome might be altered in Parkinson’s disease and related to cognitive decline. Finally, some regions of the brain might be particularly linked to cognition in Parkinson’s disease, for example, the basal forebrain.
Daniela Perani
San Raffaele University, Division of Neuroscience, San Raffaele Scientific Institute, Nuclear Medicine Unit, San Raffaele Hospital, Milan, Italy
Title: Different FDG-PET metabolic patterns in dementia syndrome (30 min)
Speaker to be announced
Title: PET imaging of tau and Aβ pathology (30 min)
Maja Trošt
University Medical Centre Ljubljana, Department for Neurology and Department for Nuclear Medicine, Ljubljana, Slovenia
Title: Different FDG-PET metabolic patterns in parkinsonian syndromes (15 min)
Tomaž Rus
Department of Neurology, University Medical Centre Ljubljana, Slovenia
Title: The role of FDG-PET in the differential diagnosis of parkinsonian syndromes (15 min)